The San Francisco 49ers vs Los Angeles Chargers preseason Week 4 showdown is one of the most anticipated games of August 2025. While the preseason doesn’t affect official standings, it offers fans and analysts an invaluable look at player development, roster decisions, and early chemistry heading into the NFL regular season.
This article breaks down:
- The key players to watch in 49ers vs Chargers based on their past performances.
- Updates on injury reports and player availability.
- Complete details on where to watch 49ers vs Chargers live on TV and streaming.
- Venue and kickoff timings for fans attending the game.
- A step-by-step guide for enjoying Week 4 preseason action.
Why 49ers vs Chargers Is a Must-Watch Game
The 49ers and Chargers share a spirited rivalry in California that always makes their matchups entertaining. Preseason or not, these two teams have plenty to prove:
- The San Francisco 49ers, fresh off multiple deep playoff runs, are trying to maintain their dominance in the NFC. Their roster is packed with elite talent and rising stars.
- The Los Angeles Chargers, led by one of the most promising quarterbacks in the league, are looking to solidify their identity in the AFC and build confidence before Week 1.
This game is the last dress rehearsal before the regular season begins, which makes it critical for starters, rookies, and bubble players.
Key Players to Watch
đź”´ San Francisco 49ers
- Brock Purdy (QB)
- Past Record: Proved himself as a reliable starter after stepping in as “Mr. Irrelevant” in 2022 and leading the 49ers to playoff success.
- Why to Watch: Coaches will want to ensure Purdy enters the season in rhythm with his star receivers.
- Christian McCaffrey (RB)
- Past Record: Dual-threat superstar who consistently ranks among the league leaders in rushing and receiving yards.
- Why to Watch: Expect limited snaps, but fans will be eager to see how McCaffrey is integrated into early offensive schemes.
- Nick Bosa (DE)
- Past Record: 2022 NFL Defensive Player of the Year, known for his game-changing pass rush.
- Why to Watch: His conditioning and preseason reps matter as he gears up for another dominant season.
⚡ Los Angeles Chargers
- Justin Herbert (QB)
- Past Record: A top-tier quarterback with multiple 4,000-yard passing seasons already under his belt.
- Why to Watch: Herbert’s preseason snaps will be crucial for building chemistry with new offensive pieces.
- Keenan Allen (WR)
- Past Record: One of the most consistent route-runners in the NFL with multiple 1,000-yard seasons.
- Why to Watch: Despite being a veteran, Allen remains a vital part of the Chargers’ offense.
- Joey Bosa (EDGE)
- Past Record: Four-time Pro Bowler, known for explosive edge rushing.
- Why to Watch: Facing his brother Nick Bosa, this matchup adds an exciting family storyline.
Player Fitness & Availability
As of August 18, 2025:
- 49ers: Brock Purdy and Christian McCaffrey are healthy, but likely to play sparingly. Nick Bosa is fit and expected to feature briefly.
- Chargers: Justin Herbert is cleared and should get early snaps. Joey Bosa remains fully fit, while veterans like Keenan Allen may have limited action to preserve health.
Both coaches will use this game to finalize depth charts while keeping their star players fresh for Week 1.
Where to Watch 49ers vs Chargers
Fans across the country will have multiple viewing options:
- NFL Network – Provides live national coverage of preseason games.
- Local TV – Bay Area and Los Angeles affiliates will carry regional broadcasts.
- NFL+ (Official Streaming) – Stream live out-of-market preseason games on smartphones, tablets, or smart TVs.
👉 Watch on NFL Network
Venue & Match Timings
- Matchup: San Francisco 49ers vs Los Angeles Chargers
- Date: Sunday, August 24, 2025
- Kickoff Time: 8:00 PM ET
- Venue: Levi’s Stadium, Santa Clara, California
Levi’s Stadium, home of the 49ers, is expected to be buzzing with energy as local fans get their final preseason glimpse of the team before the real battles begin.
Step-by-Step Guide to Follow the Game
- Check final injury reports from both teams before kickoff.
- Tune in early – Expect starting QBs Purdy and Herbert to get limited early reps.
- Watch the rookies – Preseason Week 4 is often make-or-break for rookies and undrafted players.
- Pay attention to position battles – Backup running backs, linebackers, and secondary depth are often decided in this game.
- Stay engaged on social media for instant highlights, expert breakdowns, and fan reactions.
Why This Game Matters
While the outcome won’t count in the standings, 49ers vs Chargers matters because:
- It’s the last chance for coaches to evaluate depth before Week 1.
- The Bosa brothers facing off is always a spectacle.
- Roster bubble players will be fighting desperately to secure a spot.
- Fans get an extended preview of schemes and personnel groupings.
Final Thoughts
The 49ers vs Chargers Week 4 preseason matchup offers much more than just warm-up football. From Brock Purdy and Justin Herbert’s leadership to the Bosa brothers’ battle in the trenches, this game is filled with storylines that keep fans glued to the action.
If you’re eager to see which rookies and veterans make the final cut, Levi’s Stadium is the place—or your screen via NFL Network and NFL+.
Useful Official Links
đź“Ś Disclaimer
This blog is created for informational and entertainment purposes only. Match timings, player availability, and broadcast details are accurate as of August 18, 2025, but subject to change by the NFL or official broadcasters. Fans are encouraged to verify updates directly with official team and league sources before making viewing or ticketing decisions. All images used in this article are royalty‑free or licensed for commercial use and are provided here for illustrative purposes.